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  "sourceGaps": [
    "WHO ICTRP, EU CTIS and national registries not fully integrated",
    "Registry candidate query covers DRUG/BIOLOGICAL; reviewed company projects may separately link COMBINATION_PRODUCT trials",
    "Selected official company evidence is not an exhaustive global pipeline census",
    "New asset company evidence checked 2026-10-17; existing company evidence retains 2026-10-03, 2026-10-10, 2026-10-13, 2026-10-14 and 2026-10-15 dates",
    "No global regulatory approval, territory rights or licensing availability census",
    "Targeted October 17 review: Biogen dynamic pipeline drug list was unavailable despite HTTP 200; litifilimab and dapirolizumab cards rely on readable dated official releases and ClinicalTrials.gov. AstraZeneca direct retrieval was blocked; readable official web captures were used. Targeted literature review is not full PubMed integration.",
    "Targeted October 20 evidence covers eight named assets only. Lilly direct pipeline retrieval returned HTTP403, so readable official web-tool text was used; the direct trial page returned an application shell and was not used. Viridian’s blocked IR release was replaced by its readable official company-site republication. Historical source gaps and prior evidence dates remain unchanged.",
    "Targeted 23 October evidence covers seven named assets only. The AstraZeneca volrustomig announcement returned403 on direct fetch; readable exact official text was verified through the web tool and retained in the audit. A retired Praxis URL returned404 and was replaced by readable official current pipeline and release pages. Tinengotinib was conservatively excluded pending primary-source resolution of reported China approval; it was not added as an unapproved opportunity. Prior source gaps and evidence dates remain unchanged.",
    "Targeted 26 October additions cover eight named assets only, using current ClinicalTrials.gov records and selected official company releases/pages. Direct GSK pipeline HTML did not expose candidate rows and was not used as evidence; dated GSK announcements and individual registry records support those cards. This is not a worldwide approval census or exhaustive global-registry search. Selatogrel is a manually reviewed novel drug/autoinjector COMBINATION_PRODUCT outside the unchanged broad DRUG/BIOLOGICAL query; it counts as one molecule and one reviewed trial link. All prior source gaps remain.",
    "Targeted 27 October additions cover seven named assets using current ClinicalTrials.gov query responses and selected official company/SEC/investigator disclosures. This is not an exhaustive approval or worldwide registry census. Company-reported results, subgroup or open-label observations, planned readouts and BLA/NDA review are distinguished from approval and definitive efficacy. Undated pages retain their retrieval dates, and Olema presentation month is August 2026. Licensing availability, territory rights, seller mandate and FTO remain pending verification. All pre-existing source gaps remain.",
    "Targeted 1 November additions cover six named assets with complete current ClinicalTrials.gov study objects and 12 selected company sources. Six direct company HTTP requests returned 403 (five card sources and one exclusion source); their official bodies were retrieved by the web reader and are recorded separately, without converting failed raw captures into success. The dynamic Gilead program rows were retrieved from its disclosed public pipeline endpoint. This is not a full global registry scan or exhaustive approval census. No structured results were posted in the ten selected registry records. Company-reported results, earlier-stage findings, open-label extensions and planned readouts retain those qualifications. Rights, available territories, seller mandate and FTO remain pending verification; all previous source gaps remain."
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  "contentUpdatedAt": "2026-11-11",
  "contentNote": "Registry snapshot and 393 linked trial IDs checked 11 November 2026. Eight cards carry dated registry notes covering ten trial changes, including terminated and completed history. All 97 cards and original company source dates are retained; company news was not re-researched. Retrieval dates alone are not project progress.",
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      "newRegistryTrials": 0,
      "materialRegistryChanges": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification"
    },
    {
      "date": "2026-10-13",
      "assetIds": [
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        "aglatimagene-besadenovec",
        "vk2735",
        "cretostimogene-grenadenorepvec",
        "deucrictibant",
        "navenibart",
        "olorofim"
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      "newReviewedAssets": 7,
      "existingTrialsLinked": 17,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification"
    },
    {
      "date": "2026-10-14",
      "assetIds": [
        "crb-701",
        "soquelitinib",
        "obefazimod",
        "tozorakimab",
        "zilebesiran",
        "lorundrostat",
        "povetacicept"
      ],
      "newReviewedAssets": 7,
      "existingTrialsLinked": 18,
      "additionalReviewedTrialLinksOutsideScreeningPool": [
        "NCT05742802"
      ],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification"
    },
    {
      "date": "2026-10-15",
      "assetIds": [
        "maridebart-cafraglutide",
        "bomedemstat",
        "fenebrutinib",
        "ianalumab",
        "zigakibart",
        "giredestrant",
        "xaluritamig"
      ],
      "newReviewedAssets": 7,
      "existingTrialsLinked": 44,
      "additionalReviewedTrialLinksOutsideScreeningPool": [
        "NCT07871409"
      ],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification"
    },
    {
      "date": "2026-10-17",
      "assetIds": [
        "litifilimab",
        "dapirolizumab-pegol",
        "rilvegostomig",
        "saruparib",
        "abelacimab",
        "neladalkib"
      ],
      "newReviewedAssets": 6,
      "existingTrialsLinked": 28,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification"
    },
    {
      "date": "2026-10-20",
      "assetIds": [
        "envudeucitinib",
        "trontinemab",
        "remternetug",
        "obudanersen",
        "vidofludimus-calcium",
        "elegrobart",
        "ralinepag",
        "seralutinib"
      ],
      "newReviewedAssets": 8,
      "existingTrialsLinked": 23,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and official company disclosures",
      "licensingAvailability": "pending verification",
      "countQualification": "23 registry identifiers; DIAN-TU master/arm pair is related, not two independent studies."
    },
    {
      "date": "2026-10-23",
      "assetIds": [
        "asc30",
        "inobrodib",
        "pumitamig",
        "risvutatug-rezetecan",
        "volrustomig",
        "zanzalintinib",
        "ulixacaltamide"
      ],
      "newReviewedAssets": 7,
      "existingTrialsLinked": 31,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and selected official company/SEC disclosures",
      "licensingAvailability": "pending verification",
      "countQualification": "31 registry identifiers including five combined Phase II/III records; shared extension and multi-study protocol counts are not independent pivotal-program counts."
    },
    {
      "date": "2026-10-26",
      "batchId": "2026-10-26-additions",
      "assetIds": [
        "bezuclastinib",
        "cenerimod",
        "selatogrel",
        "mocertatug-rezetecan",
        "efimosfermin-alfa",
        "velzatinib",
        "divarasib",
        "atg-022"
      ],
      "newReviewedAssets": 8,
      "existingTrialsLinked": 20,
      "additionalReviewedTrialLinksOutsideScreeningPool": [
        {
          "id": "NCT04957719",
          "assetId": "selatogrel",
          "reason": "Official COMBINATION_PRODUCT classification: investigational new drug plus autoinjector, outside the broad DRUG/BIOLOGICAL query; count one molecule and one trial."
        }
      ],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and selected official company disclosures",
      "licensingAvailability": "pending verification",
      "countQualification": "21 Phase III registry identifiers; extension/substudy links are not independent pivotal efficacy-program counts."
    },
    {
      "date": "2026-10-27",
      "batchId": "2026-10-27-additions",
      "assetIds": [
        "palazestrant",
        "vamikibart",
        "masupirdine",
        "buntanetap",
        "obexelimab",
        "bitopertin",
        "milvexian"
      ],
      "newReviewedAssets": 7,
      "existingTrialsLinked": 16,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov and selected official company, SEC and investigator disclosures",
      "licensingAvailability": "pending verification",
      "countQualification": "16 linked identifiers: 12 Phase III and four Phase II/III; extension and historical links are not independent pivotal efficacy-program counts."
    },
    {
      "date": "2026-11-01",
      "batchId": "2026-11-01-additions",
      "assetIds": [
        "fianlimab",
        "mezigdomide",
        "dazukibart",
        "ficerafusp-alfa",
        "atirmociclib",
        "anitocabtagene-autoleucel"
      ],
      "newReviewedAssets": 6,
      "existingTrialsLinked": 10,
      "additionalReviewedTrialLinksOutsideScreeningPool": [],
      "newRegistryTrials": 0,
      "source": "ClinicalTrials.gov, selected official company disclosures and the official Gilead public pipeline endpoint",
      "licensingAvailability": "pending verification",
      "countQualification": "Ten linked identifiers: nine Phase III and one Phase II/III; the open-label extension is not an independent pivotal efficacy-program count."
    }
  ]
}